Welcome to the Laboratory of Andrew Y. Koh, M.D. in the Departments of Pediatrics (Hematology/Oncology and Infectious Diseases) and Microbiology at the University of Texas Southwestern Medical Center.
We are broadly interested in understanding how resident intestinal microorganisms (particularly bacteria and fungi and collectively referred to as the gut microbiome) influence the health of human cancer and stem cell transplant patients: development of gut-derived microbial infections, graft-versus-host disease, and modulating host immune-mediated anti-tumor activity.
Our projects generally involve a mix of experimental approaches, ranging from in vitro model systems, to animal models, to advanced molecular biology techniques, next-generation sequencing approaches, and translational work with human patients. Please explore our website to find out more about the lab’s ongoing research and the people doing the work.