Identifying Microbiota and Immune Host Factors Associated With Bleeding Risk in Children With Immune Thrombocytopenia

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Saini S, Sabaeifard P, Coughlin L, Poulides N, Gan S, Zhan X, Dang M, Koh A.Y. and Zia A. (2025), Identifying Microbiota and Immune Host Factors Associated With Bleeding Risk in Children With Immune Thrombocytopenia. Am J Hematol. https://doi.org/10.1002/ajh.27669. PMID: 40110651 Abstract and Full Text.

Optimizing Precision Probiotics for Mitigating Graft-Versus-Host Disease

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Ebigbo N, Long A, Do P, Coughlin L, Poulides N, Jewell T, Gan S, Zhan X, Koh AY. Optimizing Precision Probiotics for Mitigating Graft-Versus-Host Disease. Microorganisms. 2025 Mar; 13(4):706. https://doi.org/10.3390/microorganisms13040706. Abstract and Full Text.

Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance

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Rodrigues M, Sabaeifard P, Yildiz MS, Lyon A, Coughlin L, Ahmed S, Poulides N, Toprak AC, Behrendt C, Wang X, Monogue M, Kim J, Gan S, Zhan X, Filkins L, Williams NS, Hooper LV, Koh AY, Toprak E. Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance. Cell Host Microbe. 2024 Mar 13;32(3):396-410.e6. doi: 10.1016/j.chom.2024.01.012. Epub 2024 Feb 14. PMID: 38359828; Abstract and Full Text.

Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal antitumor immunity

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Choi Y, Lichterman JN, Coughlin LA, Poulides N, Li W, Del Valle P, Palmer SN, Gan S, Kim J, Zhan X, Gao Y, Evers BM, Hooper LV, Pasare C, Koh AY. Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal antitumor immunity. Science Immunology. 2023 Mar 10;8(81):eabo2003. doi: 10.1126/sciimmunol.abo2003. Epub 2023 Mar 3. PMID: 36867675.  Abstract and Full Text.

The microbial and host factors that govern Candida gastrointestinal colonization and dissemination.

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Mishra AA, Koh AY. The microbial and host factors that govern Candida gastrointestinal colonization and dissemination. Curr Opin Microbiol. 2021 Oct;63:29-35. doi: 10.1016/j.mib.2021.05.012. Epub 2021 Jun 7.PMID: 34111679 Abstract and Full Text.

Unbiased Microbiome and Metabolomic Profiling of Fecal Samples from Patients with Melanoma.

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Bui A, Choi Y, Frankel AE, Koh AY. Unbiased Microbiome and Metabolomic Profiling of Fecal Samples from Patients with Melanoma. Methods Mol Biol. 2021;2265:461-474. doi: 10.1007/978-1-0716-1205-7_33. PMID: 33704734 Abstract and Full Text.

The gut microbiota in transplant patients

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Chong PP, Koh AY. The gut microbiota in transplant patients. Blood Rev. 2020 Jan;39:100614. doi: 10.1016/j.blre.2019.100614. Epub 2019 Aug 29.PMID: 31492463 Abstract and Full Text.

Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Efficacy in Melanoma Patients.

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Frankel AE, Coughlin LA, Kim J,  Froelich TW, Xie Y, Frenkel EP, Koh AY. Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Efficacy in Melanoma Patients. Neoplasia. 2017 Oct 19. Abstract and Full Text. 

Adaptation of Candida albicans during gastrointestinal tract colonization

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Mishra AA, Koh AY. Adaptation of Candida albicans during gastrointestinal tract colonization. Curr Clin Microbiol Rep. 2018 Sep;5(3):165-172. doi: 10.1007/s40588-018-0096-8. Epub 2018 Jun 16.PMID: 30560045  Abstract and Full Text.

Microbiota Fuels Immune Reconstitution after BMT

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Simms-Waldrip TR, Koh AY. Food for Gut: Microbiota Fuels Immune Reconstitution after BMT. Cell Host Microbe. 2018 Apr 11;23(4):423-424. doi: 10.1016/j.chom.2018.03.015.PMID: 29649435 Abstract and Full Text.