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Utility of in vivo transcription profiling for identifying Pseudomonas aeruginosa genes needed for gastrointestinal colonization and dissemination.

Koh AY, Mikkelsen PJ, Smith RS, Coggshall KT, Kamei A, Givskov M, Lory S, Pier GB. Utility of in vivo transcription profiling for identifying Pseudomonas aeruginosa genes needed for gastrointestinal colonization and dissemination. PLoS ONE, 2010 Dec 10; 5(12): e15131. PMID: 21170272. Abstract and Text

Analysis of Acquisition of Pseudomonas aeruginosa Gastrointestinal Mucosal Colonization and Horizontal Transmission in a Murine Model.

Kamei A*, Koh AY*, Gadjeva M, Priebe GP, Lory S, Pier GB. Analysis of Acquisition of Pseudomonas aeruginosa Gastrointestinal Mucosal Colonization and Horizontal Transmission in a Murine Model. Journal of Infectious Diseases. 2010 Jan; 201(1):71-80. PMID: 19938976 * Both authors contributed equally to this work. Abstract and Full Text

Inescapable need for Neutrophils as Mediators of Cellular Innate Immunity to Acute Pseudomonas aeruginosa Pneumonia.

Koh AY, Priebe GP, Ray C, Van Rooijen N, Pier GB. Inescapable need for Neutrophils as Mediators of Cellular Innate Immunity to Acute Pseudomonas aeruginosa Pneumonia. Infection and Immunity.   2009 Dec; 77(12):5300-5310. PMID: 19805527. Abstract and Full Text

Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes.

van Gennip M, Christensen LD, Alhede M, Phipps R, Jensen PO, Christophersen L, Pamp SJ, Moser C, Mikkelsen PJ, Koh AY, Tolker-Nielsen T, Pier GB, Hoiby N, Givskov M, Bjarnsholt T. Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes. Acta Pathologica, Microbiologica et Immunologica Scandinavica 2009 Jul; 117:537-46. PMID:19594494. Abstract and Full Text

Mucosal damage and neutropenia are required for Candida albicans dissemination.

Koh AY, Köhler JR, Coggshall KT, Van Rooijen N, Pier GB. Mucosal damage and neutropenia are required for Candida albicans dissemination. PLoS Pathogens 2008; 4(2):e35 PMID:18282097. Abstract and Full Text

Virulence of Pseudomonas aeruginosa in a murine model of gastrointestinal colonization and dissemination in neutropenia.

Koh AY, Priebe GP, Pier GB. Virulence of Pseudomonas aeruginosa in a murine model of gastrointestinal colonization and dissemination in neutropenia.  Infection and Immunity 2005 Apr ; 73(4):2262-2272. PMID: 15784570. Abstract and Full Text